Rare Disease
- Problem
- A specialty pharma client needed to position a rare disease therapy across fragmented evidence and divergent payer environments.
- Method
- Mixed-methods evidence synthesis combining systematic literature review with stakeholder interviews across three regions.
- Insight
- Identified a consistent unmet-need signature that anchored the payer narrative and harmonised regional messaging.
- Outcome
- Submission pack accepted in first review cycle; informed market access strategy across two additional markets.